在冠状动脉疾病中通过心率变化评估心理压力
Prashant Kumar1, Gourav Bhattacharya2, Mrinal Kunj1
1Department of Cardiology, RIMS, Ranchi, Jharkhand, India.
Journal of pharmacy & bioallied sciences
|January 12, 2026
概括
心理压力显著影响冠状动脉疾病 (CAD) 患者,降低心率变化 (HRV) 并表明自主失衡. 这凸显了管理压力的必要性,以改善心脏健康.
科学领域:
- 心脏病学 心脏病学
- 自主神经系统研究 自主神经系统研究
- 心理生理学 心理生理学
背景情况:
- 冠状动脉疾病 (CAD) 与生理和心理压力有关,影响心脏自主控制.
- 心率变化 (HRV) 作为自主神经系统功能和压力水平的关键非侵入性指标.
研究的目的:
- 研究冠状动脉疾病 (CAD) 患者感知心理压力和心率变化 (HRV) 之间的关系.
- 评估不同压力水平如何与CAD患者的特定HRV参数相关.
主要方法:
- 一项涉及100名CAD患者的横截面观察性研究.
- 使用感知压力量表 (PSS-10) 评估的心理压力.
- 通过心电图测量心率变化 (HRV),分析时间域 (SDNN,RMSSD) 和频域 (LF,HF,LF/HF比率) 参数.
主要成果:
- 38%的参与者报告了高压力水平.
- 在高压力与低压力组中观察到显著较低的SDNN和RMSSD值 (P < 0.001).
- 在高压力组中发现了更高的LF/HF比率,PSS得分和RMSSD之间存在强烈的负相关性 (r = -0.68,P < 0.001).
结论:
- 在CAD患者中,心理压力会导致HRV的显著变化.
- 研究结果表明,压力严重的CAD患者的副交感活动减少和自主失调.
- HRV分析对于了解压力对心脏自主功能在CAD中的影响至关重要.
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