银二胺化物在阻止3-6岁儿童下的有效性协议:一个基于社区的随机对照试验
Swati Sharma1, Ajoy Kumar Shahi2, Sonal Saigal3
1Department of Pedodontic and Preventive Dentistry, Dental Institute, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, India.
Journal of pharmacy & bioallied sciences
|January 12, 2026
概括
银二胺化物 (SDF) 和玻璃离子体水泥 (GIC) 进行比较,用于治疗印度学龄前儿童的幼儿. 这项研究将确定SDF是否是公共卫生计划中具有成本效益的,最少侵入性的选择.
科学领域:
- 儿科牙科 儿科牙科
- 公共卫生 公共卫生
- 皮肤病学 皮肤病学 皮肤病学
背景情况:
- 幼儿牙是一个重大的公共卫生挑战,特别是在农村和部落印度社区.
- 银胺化物 (SDF) 提供了一种非侵入性,负担得起的方法来阻止幼儿牙损伤.
- 这项研究侧重于38%的SDF与高化物玻璃离子体水泥 (GIC) 对学龄前儿童活跃牙损伤的有效性.
研究的目的:
- 评估38%的SDF在在学龄前儿童中阻止活跃牙损伤的有效性.
- 为了比较SDF与高化物GIC的虫止能力.
- 评估SDF是否适合在资源有限的环境中融入国家口腔健康计划.
主要方法:
- 一个长达24个月的平行组,分层集群随机对照试验,涉及400名3-6岁儿童.
- 被诊断为ICDAS评分5或6的活跃病变的参与者将从兰的Angara区的Anganwadi中心招募.
- 儿童将随机分为两组:38%的SDF (干预) 或高化物GIC (控制),在6,12,18和24个月后进行评估.
主要成果:
- 与GIC相比,在社区环境中,SDF在阻止虫的预期可比或更高的疗效与GIC相比.
- 数据分析将集中在使用ICDAS标准和视觉触觉评估的空停止率上.
- 该研究旨在提供证据,证明SDF在现实社会环境中的有效性.
结论:
- 银二胺化物 (SDF) 预计将成为早期儿童虫的高效,最小侵入性治疗方法.
- 结果将支持在公共卫生倡议中采用SDF,用于服务不足地区的幼儿.
- 这项研究有助于基于证据的策略,在资源有限的环境中管理牙.
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