银胺化物和纳米银化物的有效性预防:一项比较研究
Priyatam Karade1, Sameep Singh2, Neeti Mittal3
1Department of Conservative Dentistry and Endodontics, Bharati Vidyapeeth, (Deemed To Be University) Dental College and Hospital, Sangli, Maharashtra, India.
Journal of pharmacy & bioallied sciences
|January 12, 2026
概括
银胺化物 (SDF) 和纳米银化物 (NSF) 能够有效地预防儿童的牙. 与水相比,这两种治疗方法都显著减少了,而SDF显示出略有优异的结果.
科学领域:
- 牙科 牙科是指牙科的专业.
- 儿科牙科 儿科牙科
- 牙 预防 预防 牙
背景情况:
- 牙损是全球主要的健康问题,特别是在儿童中.
- 银二胺化物 (SDF) 是一个已被证明的虫止剂.
- 纳米银化物 (NSF) 是一种新的配方,具有潜在的抗菌和重矿性质.
研究的目的:
- 为了比较SDF和NSF在儿童中预防的疗效.
- 评估SDF和NSF与对照组的有效性.
主要方法:
- 一项随机,双盲,受控的临床试验与90名脏活跃儿童 (6-9岁) 进行.
- 参与者被分配接受38%的SDF,NSF或蒸水 (控制).
- 皮经验 (DMFS) 在基线,6个月和12个月被评估.
主要成果:
- 12个月后,与对照组相比,SDF和NSF组的DMFS增幅明显较低 (分别P < 0.001和P = 0.003).
- 在SDF和NSF之间的疗效差异没有统计学意义 (P = 0.217).
- SDF组的平均DMFS增幅为0.8±1.2,NSF组为1.1±1.3,对照组为2.7±1.5.
结论:
- 在高风险儿童中,SDF和NSF都能有效地预防脏病的进展.
- 虽然在统计学上不显著,但SDF的疗效略高于NSF.
- NSF为空管理提供了一个有前途的替代方案,其结果与SDF相似.
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