在青少年的口腔粘膜变化的评估 烟者:一个临床和细胞病理学研究
Nishath S Abdul1, Mahesh Shenoy2, Sahana Shivakumar3
1Department of OMFS and Diagnostic Sciences, Faculty of Oral Pathology, Riyadh Elm University, Riyadh 11681 Kingdom of Saudi Arabia.
Journal of pharmacy & bioallied sciences
|January 12, 2026
概括
青少年使用无烟烟草会导致口腔粘膜的显著变化,包括癌前病变. 通过查和戒烟计划进行早期检测对于预防年轻吸烟者的口腔癌至关重要.
科学领域:
- 口腔病理学 口腔病理学
- 公共卫生 公共卫生
- 青少年医学 青少年医学
背景情况:
- 在印度的青少年中,无烟烟草的使用是一个重要的公共卫生问题.
- 早期和慢性暴露于烟草可以导致病态的口腔粘膜变化,可能导致恶性瘤.
- 这项研究旨在评估青少年无烟烟草使用者的口腔粘膜变化.
研究的目的:
- 在临床和细胞病理学上评估青少年无烟口香烟的口腔粘膜变化.
- 为了识别与青少年吸烟相关的潜在恶性疾病的早期标志物.
- 为了确定无烟烟草消费与上皮异常之间的相关性.
主要方法:
- 采用了横截面研究设计,包括青少年吸烟者和年龄匹配的对照组.
- 进行了临床检查,以确定可见的粘膜变化.
- 皮细胞学被用来检测细胞缺陷,使用帕帕尼科劳标准进行分级.
主要成果:
- 76%的青少年吸烟者表现出临床的口腔粘膜变化,如多色素和白血.
- 在52%的青少年吸烟者中观察到细胞学性异常 (帕帕尼科劳II-V级).
- 在无烟烟草使用和上皮细胞变化之间发现了强烈的相关性,只有8%的对照显示轻度炎症.
结论:
- 在青少年无烟烟草使用者中,早期的口腔粘膜变化很普遍.
- 这些发现强调了针对青少年进行有针对性的预防性查和戒烟干预措施的迫切需要.
- 迅速采取行动可以缓解潜在恶性疾病的进展,降低口腔癌的风险.
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