基于CT的纹理分析在未确定的儿科脏和副脏群体中
Stuti Chandola1, Priyanka Naranje1, Arun Kumar Gupta1
1Department of Radiodiagnosis and Interventional Radiology, All India Institute of Medical Sciences, New Delhi, India.
The Indian journal of radiology & imaging
|January 12, 2026
概括
基于CT的纹理分析 (CTTA) 在将儿科威尔姆斯瘤与神经母细胞瘤区分开来方面显示出前景. 这种技术还可以区分神经母细胞瘤亚型,包括MYCN增强的病例.
科学领域:
- 放射学 放射学是指放射学
- 在瘤学瘤学.
- 医疗成像医学成像
背景情况:
- 使用常规CT将儿科威尔姆斯瘤与神经母细胞瘤区分开来是具有挑战性的,特别是在大型瘤中.
- 准确的区分对于适当的治疗计划和患者的结果至关重要.
研究的目的:
- 评估基于CT的纹理分析 (CTTA) 在区分儿科威尔姆斯瘤与神经母细胞瘤方面的有效性.
- 评估CTTA区分神经母细胞瘤组织学亚型的能力,包括MYCN增强的病例.
主要方法:
- 从未接受过治疗的儿科患者 (<18岁) 进行对比度增强的CT扫描的回顾性分析,这些患者患有脏/副脏瘤.
- 纹理分析软件的应用以提取一级纹理特征 (平均值,方差,斜率,曲率) 和灰度特征.
- 使用曼·惠特尼U和费舍尔精确测试的统计分析,p < 0.05被认为是显著的.
主要成果:
- 与威尔姆斯瘤相比,神经母细胞瘤的瘤更频繁地与化和转移有关.
- 神经母细胞瘤的内损伤变异明显高于威尔姆斯瘤.
- 经MYCN增强的神经母细胞瘤的内损伤平均值高于未增强的瘤 (p < 0.05).
结论:
- CTTA显示出在将儿科威尔姆斯瘤与神经母细胞瘤区分开来方面的潜力.
- CTTA可能有助于区分神经母细胞瘤组织学亚型和识别MYCN增强神经母细胞瘤.
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