非霍奇金淋巴瘤和结核在同一个宫淋巴结中共存:一个病例报告
Abdallah Taha1, Sara Alzhrani2, Nawaf Aljafari2
1General Surgery Department, Faculty of Medicine, South Valley University, Qena, EGY.
Cureus
|January 12, 2026
概括
一个宫质量揭示了共存的扩散大B细胞淋巴瘤 (DLBCL) 和结核淋巴腺炎. 及时诊断和使用抗结核疗法 (ATT) 和化疗的连续治疗导致完全缓解.
科学领域:
- 在瘤学瘤学.
- 传染性疾病 传染性疾病
- 病理学 病理学 病理学
背景情况:
- 宫质量可能会带来诊断挑战,可能掩盖并发性疾病.
- 结核性淋巴腺炎是部质量的常见原因,特别是在特有地区.
- 淋巴瘤和结核在淋巴结中的共存需要仔细的诊断考虑.
研究的目的:
- 报告一种罕见的同时扩散的大B细胞淋巴瘤 (DLBCL) 和结核淋巴腺炎的病例.
- 强调彻底的宫淋巴腺病变的组织病理学和分子评估的重要性.
- 突出共存恶性瘤和感染的诊断和治疗影响.
主要方法:
- 宫质量的切除活检,然后进行组织病理学检查.
- 实验室分析包括结核病和结核病培养的聚合酶链反应 (PCR).
- 免疫组织化学验证DLBCL,评估标记物如CD20,BCL6,MUM1和Ki-67.
主要成果:
- 活检显示了扩散型大B细胞淋巴瘤 (DLBCL) 和结核淋巴腺炎.
- 免疫组织化学证实DLBCL具有较高的扩散指数 (Ki-67 80%).
- 患者在连续的抗结核疗法 (ATT) 和R-CHOP化疗后实现了完全缓解.
结论:
- 淋巴瘤和结核淋巴腺炎可以同时发生在同一个淋巴结中.
- 怀疑肺结核的患者接受淋巴结活检时,必须对潜在的淋巴瘤进行评估.
- 同时存在的恶性瘤需要一个定制的治疗策略,涉及医疗瘤专家.
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