一个由 thiazide 诱导的胰腺炎病例
Abdulla Almajed1, Shooq Alsebaie2, Nora McVinnie1
1Internal Medicine, Henry Ford Health System, Detroit, USA.
Cureus
|January 12, 2026
概括
这一案例突显出一种罕见的急性胰腺炎病例,这种病例是由一种 thiazide 利尿剂引起的. 仔细的药物检查对于在没有常见原因的情况下识别药物诱导的胰腺炎至关重要.
科学领域:
- 胃肠病学 胃肠病学
- 内部医学 内部医学
- 药理学 药理学是指药理学的学科.
背景情况:
- 急性胰腺炎通常是由胆结石或酒精引起的,当典型病因不存在时,它会构成诊断挑战.
- 识别不太常见的原因,如药物诱导的胰腺炎,对于有效的患者管理至关重要.
- 这起案件涉及一名72岁的妇女,患有多种并发症,呈现急性胰腺炎.
研究的目的:
- 为了调查一种罕见的急性胰腺炎病例,该病例发生在没有可识别的常见原因的患者身上.
- 强调在诊断药物诱导胰腺炎时彻底调和药物的重要性.
- 突出在临床实践中对不常见病因的高怀疑指数的需要.
主要方法:
- 进行了全面的检查,包括实验室测试 (脂酶,脂质资料,自身免疫抗体,,甘油三) 和成像 (腹部CT扫描).
- 排除性诊断标准被应用,以排除急性胰腺炎的常见原因和其他罕见原因.
- 仔细审查了患者的药物 anamnesis,包括氨酸,安洛迪平,洛萨坦和阿皮克萨班.
主要成果:
- 患者表现出严重的胃上部疼痛和升高的脂酶水平,与急性胰腺炎一致.
- 图像检查排除了胆结石,胰腺缩,区域静脉血栓和恶性瘤.
- 广泛的工作排除了自身免疫性疾病,高血症,高甘油三血症,创伤,子刺和ERCP后胰腺炎.
结论:
- 提亚齐德利尿剂的使用被确定为急性胰腺炎的可能原因.
- 这一案例强调了在患有异常性急性胰腺炎的患者中考虑药物诱导的胰腺炎,特别是提亚诱导的胰腺炎的重要性.
- 准确的药物协调和高的怀疑指数对于诊断急性胰腺炎的罕见原因至关重要.
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