评估在移植后患者中复发性急性鼻炎的发展:关于鼻外科手术必要性的研究
Estephania Candelo1,2, Anyull Dayanna Bohorquez-Caballero1, Angela M Donaldson1
1Department of Otolaryngology and Head-Neck Surgery Mayo Clinic Jacksonville Florida USA.
OTO open
|January 12, 2026
概括
复发性急性鼻炎 (RARS) 影响了近10%的移植接受者 (TR). 预先存在的疾病,如类风湿性关节炎增加RARS风险,但很少需要手术.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 免疫学 免疫学 免疫学
- 移植医学 移植医学 移植医学
背景情况:
- 复发性急性鼻炎 (RARS) 严重影响生活质量.
- 移植接收者 (TR) 面临着对鼻状况的高度脆弱性.
- 目前缺乏TR中RARS的管理指南.
研究的目的:
- 为了确定移植受体中RARS的患病率.
- 为了确定与移植后RARS发展相关的风险因素.
- 在这个人群中评估RARS手术干预的必要性.
主要方法:
- 从2017-2022年对1116名患者进行了回顾性队列研究.
- 根据RARS诊断和鼻手术频率对患者进行了分类.
- 后勤回归分析确定了RARS发展的几率比率.
主要成果:
- 9.95%的移植接受者患上了RARS.
- 移植前的喘,病毒感染和类风湿性关节炎 (RA) 在RARS患者中更常见.
- 关节炎,中性衰竭和地幔细胞淋巴瘤在移植后增加了RARS的可能性.
结论:
- 这项研究是第一个研究RARS发病率和TR的预测因素的研究.
- 移植前的并发症增加了RARS风险,但不一定需要手术.
- 在TR中RARS的管理需要进一步的研究,手术干预的门很低.
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