在一般日本人口中,脉冲率变化和全因死亡风险在一般日本人口中变化
Isao Saito1, Koutatsu Maruyama2, Tadahiro Kato3
1Department of Public Health and Epidemiology, Faculty of Medicine, Oita University Oita Japan.
Circulation reports
|January 12, 2026
概括
低脉率变化 (PRV) 表明日本一般人口的死亡风险较高. 来自PRV的自主功能参数是所有原因死亡率的重要预测因素.
科学领域:
- 心脏病学 心脏病学
- 自主神经系统研究 自主神经系统研究
- 公共卫生 公共卫生
背景情况:
- 脉率变异性 (PRV) 被探索为评估自主功能时的心率变异性的替代品.
- 在一般人群中,PRV衍生参数对死亡率的预测值仍然不清楚.
研究的目的:
- 调查PRV衍生参数是否预测日本一般人口的全因死亡风险.
- 检查自主功能标志物与死亡结果之间的关联.
主要方法:
- 一项针对5943名日本人 (30-79岁) 的前性研究持续了12.4年.
- 脉冲波分析使用光电脉冲扫描来评估PRV和静止心率 (RHR).
- 用于分析与PRV参数相关的死亡风险的Cox比例危险模型和处罚立方线.
主要成果:
- 在随访期间记录了437例死亡.
- 正常到正常间隔 (SDNN) 标准偏差的最低四分位数显示死亡风险增加了1.51.
- PRV参数显示了与死亡风险的显著非线性关联,即使经过对混因素和RHR进行调整.
结论:
- 减少PRV衍生的自主性参数与所有原因死亡率的风险增加有关.
- 在一般人群中,PRV分析为自主功能和死亡率预测提供了有价值的见解.
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