在中国人群中,双腹与三腹动脉之间左心室重塑的差异与大动脉狭窄的三腹动脉之间,经过透气管大动脉置换后的中国人群
Chengwei Chi1, Jiaqi Zhang2, Weilong Zhao1
1Department of Cardiology, Affiliated Zhongshan Hospital of Dalian University, 116001 Dalian, Liaoning, China.
Reviews in cardiovascular medicine
|January 12, 2026
概括
通过导管的大动脉置换 (TAVR) 在长期双大动脉 (BAV) 和三大动脉 (TAV) 患者中显示出类似的左心室重塑. 在TAVR后的BAV患者中,短期逆转改造可能较少.
科学领域:
- 心脏病学 心脏病学
- 心脏外科手术 心脏外科手术
- 生物医学工程 生物医学工程
背景情况:
- 大动脉狭窄 (AS) 需要干预,跨导管大动脉置换 (TAVR) 是关键的治疗方法.
- 双主动脉 (BAV) 和三主动脉 (TAV) 代表了AS的不同的病因.
- 了解BAV与TAV患者的逆左心室 (LV) 改造后TAVR的差异对于优化结果至关重要.
研究的目的:
- 为了比较在中国患者中TAVR后的反向LV重塑,BAV与TAV.
- 为了确定有利的中期LV反向改造TAVR后的预测因素.
主要方法:
- 对137名患者进行自扩展维纳斯A门的TAVR的回顾性分析.
- 在基线和TAVR后至少6个月内进行心声谱随访.
- 在BAV和TAV组之间对LV质量指数 (LVMi) 变化进行比较.
主要成果:
- 与TAV患者相比,BAV患者更年轻,大动脉根直径 (ARD) 更大.
- 在BAV患者中,短期 (1个月) 的反向LV重塑似乎不那么明显 (p=0.044).
- 在TAVR后6个月,没有观察到LVMi的显著差异.
- 较高的TAVR前平均压力梯度 (MPG) 和ARD与有利的中期LV反向重塑有关.
- 更严重的AS与有利的中期LV反向改造相关.
结论:
- 虽然TAVR后BAV患者的短期反向LV重塑可能较小,但中期结果与TAV患者相似.
- 程序前的因素,如MPG,ARD和AS严重程度预测有利的LV反向改造TAVR后.
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