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Updated: Jan 13, 2026

A Reporter Based Cellular Assay for Monitoring Splicing Efficiency
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在狼中性粒细胞中U12型分离的失调

Luz P Blanco1, Binod Regmi2, Carmelo Carmona-Rivera1

  • 1Systemic Autoimmunity Branch, the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Bethesda, Maryland, USA.

Arthritis & rheumatology (Hoboken, N.J.)
|January 12, 2026
PubMed
概括

系统性红斑狼 (SLE) 中性粒细胞由于轻微的结合体缺陷影响NADPH氧化酶 (Nox) 活性而表现出功能受损. 低密度粒细胞 (LDG) 的这些拼接异常与狼病活动相关.

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