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Updated: Jan 13, 2026

Monitoring Hippo Signaling Pathway Activity Using a Luciferase-based Large Tumor Suppressor LATS Biosensor
07:16

Monitoring Hippo Signaling Pathway Activity Using a Luciferase-based Large Tumor Suppressor LATS Biosensor

Published on: September 13, 2018

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异常的Hippo-YAP/TEAD信号驱动在外部听道状细胞癌中恶性转录重编程

Kuniaki Sato1, Noritaka Komune2, Mayumi Ono2

  • 1University of California, San Diego La Jolla, California United States.

Cancer research communications
|January 12, 2026
PubMed
概括

这项研究表明,YAP/TEAD通路在外部听道状细胞癌 (EACSCC) 中过度活跃,推动瘤生长. 用抑制剂向这种途径显示出治疗这种罕见癌症的前景.

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