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Updated: Jan 14, 2026

Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production
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在人类肠道上皮细胞中,基底IFNλ2/3信号是ISG表达和病毒控制所需的

Yagmur Keser1, Zehra Sena Bumin1, Amelia Perez Valiente1

  • 1Department of Molecular Genetics and Microbiology, University of Florida, College of Medicine, Gainesville, Florida, United States of America.

PLoS pathogens
|January 12, 2026
PubMed
概括

基础干扰素-lambda 2/3 (IFNλ2/3),而不是IFNλ1,对于限制肠道中各种病毒感染至关重要. 这种亚型通过调节干扰素刺激的基因和膜信号来增强表皮抗病毒防御.

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