人类太空飞行后的大脑移位和非线性变形
Tianyi Wang1, Rouglas J Odor1, Yiri E De Dios2
1Department of Applied Physiology and Kinesiology, University of Florida, Gainesville, FL 32611.
概括
宇航员在太空中经历了显著的大脑转移和变形,在头骨内向上和向后移动. 在微重力类型中观察到的这些变化与暴露时间和飞行后的影响平衡相关.
科学领域:
- 神经科学是一个神经科学.
- 太空医学 太空医学
- 人体生理学 人体生理学
背景情况:
- 太空飞行改变了人体内的液体分布,包括大脑.
- 以前的研究指出,大脑的平均位置发生了变化,但详细的区域变化尚不清楚.
研究的目的:
- 在太空飞行和床上休息后量化大脑区域变化和变形.
- 为了研究这些大脑变化的行为相关性.
- 为了比较太空飞行效果与向下倾斜的卧床休息模拟.
主要方法:
- 分析了26名宇航员和24名卧床参与者的MRI数据.
- 刚性身体登记测量大脑相对于头骨的位置变化.
- 量化区域变形和与暴露持续时间和行为相关的相关性.
主要成果:
- 大脑向后移动,向上移动,并在太空飞行/床上休息后旋转,与持续时间相关联.
- 观察到非线性区域变形和对称的左向右转移.
- 补充运动皮层在太空一年后显示出最大的向上移位 (2.52毫米).
- 飞行后6个月内恢复,后部岛屿移位与平衡下降相关.
结论:
- 太空飞行会导致大脑在头骨区内发生全面的脑部变化和变形.
- 这些变化在一定程度上被头向下倾斜的卧床模仿,但显示出明显的差异.
- 这些发现对于了解太空飞行对大脑结构,功能和行为的影响至关重要.
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