相关实验视频

Updated: Jun 29, 2026

Detection of a Circulating MicroRNA Custom Panel in Patients with Metastatic Colorectal Cancer
08:12

Detection of a Circulating MicroRNA Custom Panel in Patients with Metastatic Colorectal Cancer

Published on: March 14, 2019

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以机器学习为指导,对转移相关的miRNAs进行识别,并将其整合到基于PFI的cox风险评分和nomogram中

Ahmed A Emam1, Mohamed Y Foda2, Manar Refaat2

  • 1Department of Chemistry, Biochemistry Division, Faculty of Science, Mansoura University, Mansoura, 35516, Egypt; Medical Experimental Research Centre (MERC), Faculty of Medicine, Mansoura University, Mansoura, 35516, Egypt.

Computers in biology and medicine
|January 12, 2026
PubMed
概括

这项研究确定了四个微RNA (miRNA) 签名,可以预测乳腺癌的转移,并开发出诊断的临床工具. 这些发现突出了早期检测和治疗指导的潜在液体活检生物标志物.

关键词:
生物标志物 生物标志物乳腺新生体的形成.机器学习 机器学习微RNAs是一种微RNA.新生体转移的转移.预测 预后 预测 预测瘤是一个瘤.

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相关概念视频

MicroRNAs01:22

MicroRNAs

MicroRNA (miRNA) are short, regulatory RNA transcribed from introns—non-coding regions of a gene—or intergenic regions—stretches of DNA present between genes. Several processing steps are required to form biologically active, mature miRNA. The initial transcript, called primary miRNA (pri-mRNA), base-pairs with itself forming a stem-loop structure. Within the nucleus, an endonuclease enzyme, called Drosha, shortens the stem-loop structure into hairpin-shaped pre-miRNA. After the pre-miRNA ends...
MicroRNAs01:22

MicroRNAs

MicroRNA (miRNA) are short, regulatory RNA transcribed from introns—non-coding regions of a gene—or intergenic regions—stretches of DNA present between genes. Several processing steps are required to form biologically active, mature miRNA. The initial transcript, called primary miRNA (pri-mRNA), base-pairs with itself forming a stem-loop structure. Within the nucleus, an endonuclease enzyme, called Drosha, shortens the stem-loop structure into hairpin-shaped pre-miRNA. After the pre-miRNA ends...
MicroRNAs01:22

MicroRNAs

MicroRNA (miRNA) are short, regulatory RNA transcribed from introns (non-coding regions of a gene) or intergenic regions (stretches of DNA present between genes). Several processing steps are required to form biologically active, mature miRNA. The initial transcript, called primary miRNA (pri-mRNA), base-pairs with itself, forming a stem-loop structure. Within the nucleus, an endonuclease enzyme, called Drosha, shortens the stem-loop structure into hairpin-shaped pre-miRNA. After the pre-miRNA...