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pH对小分子抑制剂与流感病毒血素结合的作用

Varada Anirudhan1, Irina Gaisina2, Amir Shimon3

  • 1Department of Microbiology and Immunology, University of Illinois Chicago, Chicago, IL, 60612, USA.

The Journal of biological chemistry
|January 12, 2026
PubMed
概括

针对A型流感病毒血蛋白的新型小分子抑制剂在较低的pH值时显示出较高的结合亲和力. 这种依赖pH值的机制对于开发有效的抗流感抗病毒疗法至关重要.

关键词:
抗病毒药物 抗病毒药物聚变抑制剂 聚变抑制剂血凝氨酸是什么 血凝氨酸流感病毒是流感的病毒.它们的作用机制.表面的等离子体共振.热转移测试试验 热转移测试

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