治疗气体作为口腔疾病的新兴治疗方法
Ann Badia1, Jihyuk Yang2, Sara Aliyeva3
1Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, PA 15213, USA.
Advanced drug delivery reviews
|January 12, 2026
概括
基于气体的疗法为口腔疾病提供了最少的侵入性方法,克服了传统治疗的局限性. 正在开发创新的交付系统,以克服挑战,并加强临床翻译,以获得更好的牙科护理.
科学领域:
- 生物材料科学 生物材料科学
- 牙科治疗学 牙科治疗学
- 气体疗法是一种天然气疗法.
背景情况:
- 传统的牙科治疗面临诸如生物膜难以进入和抗菌素耐药性等挑战.
- 治疗气体为治疗口腔疾病提供了一个有前途的替代方案.
- 现有的方法在组织再生和有针对性的输送方面扎.
研究的目的:
- 探索基于口腔气体的治疗方法在治疗各种牙科疾病方面的潜力.
- 审查不同治疗气体在牙科中的生物效应和应用.
- 确定临床翻译的障碍,并提出创新的交付解决方案.
主要方法:
- 对口服应用中的治疗气体现有文献的审查.
- 对O2,O3,NO,H2等气体独特的生物效应的分析.
- 研究包括纳米平台和水凝在内的新型输送系统.
主要成果:
- 治疗气体具有抗微生物,抗炎和再生性质.
- 像纳米平台和水凝这样的创新输送系统显示出控制气体释放的前景.
- 挑战包括剂量控制,潜在的毒性和输送系统的限制.
结论:
- 基于气体的疗法具有很大的潜力,可以作为常规牙科治疗的辅助或替代方案.
- 对安全,患者友好的输送技术和临床试验的进一步研究至关重要.
- 建立一个明确的监管框架对于广泛的临床采用至关重要.
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