睡眠和双相情感障碍:与分娩和新生儿结局的关联
Sanne M Hendriks1, Anja W M M Stevens1, Bart Geerling2
1Centre for Bipolar Disorder, Dimence Mental Health Institute, Deventer, Netherlands, Pikeursbaan 3, 7411 GT, Deventer, the Netherlands.
Journal of affective disorders
|January 12, 2026
概括
在患有双相情感障碍的孕妇中,第二季度睡眠时间较短与剖腹产风险较高有关,尽管不显著. 睡眠障碍对母亲健康和产后风险至关重要.
科学领域:
- 围产期心理健康问题
- 睡眠的药物 睡眠的药物
- 生殖精神病学是一种精神病学.
背景情况:
- 怀孕期间的双极性障碍 (BD) 对母亲和新生儿的福祉构成独特的挑战.
- 了解睡眠障碍对这一群体的影响对于有效管理至关重要.
- 以前的研究还没有广泛探索睡眠模式及其与孕妇和新生儿产科结果的相关性.
研究的目的:
- 调查怀孕期间睡眠时间和睡眠质量与分娩/新生儿结果之间的关系.
- 评估怀孕妇女的睡眠参数,诊断出患有双相情感障碍.
- 确定睡眠障碍与产科或新生儿不良事件之间的潜在联系.
主要方法:
- 对65名荷兰孕妇进行前性队列研究 (Sleepreg-双极障碍 - Sleepreg-BD).
- 通过动图评估睡眠质量;使用睡眠日记测量睡眠持续时间.
- 躁狂和抑郁症状的严重程度使用阿尔特曼自我评价躁狂尺度 (ASRM) 和抑郁症状快速清单 (QIDS) 进行评估.
主要成果:
- 第二季度的平均睡眠效率为76.95%,第三季度为74.8%.
- 平均睡眠时间在第二季度为408.95分钟,第三季度为412.18分钟.
- 妊娠第二季度睡眠时间缩短显示了剖腹产风险增加的趋势,但经过对混因素进行调整后,这一趋势在统计学上并不显著. 对于分娩或新生儿结局,没有发现其他显著的关联.
结论:
- 虽然睡眠障碍与分娩/新生儿结局之间的直接关联在这个队列中基本上无意义,但睡眠问题仍然具有临床意义.
- 怀孕期间的睡眠障碍需要在患有BD的妇女中注意母亲的健康.
- 解决睡眠问题对于减轻这一群体产后精神病风险很重要.
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