2025年不良事件的存在学
Chenchen Pan1, Qiuyue Yang1, Xue Zhang1
1School of Life Health Information Science and Engineering, Chongqing University of Posts and Telecommunications, Chongqing, China.
不良事件本体学 (OAE) 已大幅扩展,自2014年以来增加了7741个新术语. 这增强了对不良事件数据的标准化和整合,以改善临床研究.
科学领域:
- 生物医学信息学 生物医学信息学
- 临床研究术语学术语.
背景情况:
- "不良事件本体学" (OAE) 于2011年建立,以标准化不良事件 (AE) 的定义.
- 在各种AE调查中,OAE已经成功地被应用,因此需要不断扩展.
研究的目的:
- 记录对OAE的实质性本体扩展,重点关注患者的解剖区域和临床表现.
- 报告OAE目前的规模和增长情况,强调其增加的临床细节性和领域覆盖范围.
主要方法:
- 对OAE当前任期数的统计分析和与以前的出版物进行比较.
- 本体扩展的文档,包括症状,身体征兆,病理过程,给药途径,剂量和人口统计数据.
主要成果:
- 现在,OAE包括10,829个正式定义的术语,自2014年出版以来增加了7,741个新术语.
- 实体学扩展涵盖了患者的解剖区域,临床表现 (症状,征兆,病理),以及管理途径和人口统计等决定因素.
结论:
- 扩展的OAE为不良事件数据提供了增强的临床细节性和领域覆盖.
- OAE的标准化语义架构促进了AE模式,病因因素和临床结果的跨学科分析.
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