丹迪-沃克综合征与水脑经历VPS或CPS? 一个单一中心的回顾性研究
Zhiqiang Liu1,2, Bei Liu1,2, Chaoqun Weng1,2
1Department of Neurosurgery, Sanbo Brain Hospital, Capital Medical University, Beijing, 100093, China.
概括
静脉皮管突变 (VPS) 可能比囊管突变 (CPS) 提供更好的结果,用于治疗与丹迪-沃克综合征 (DWS) 相关的儿童水. 良好的小脑虫子发育与积极的手术结果密切相关.
科学领域:
- 儿科神经外科 儿科神经外科
- 发育神经学 发育神经学
- 手术结果研究研究.
背景情况:
- 丹迪-沃克综合征 (DWS) 经常与水头同时发生,需要手术干预.
- 在DWS中治疗水脑的最佳手术方法,特别是比较横向心室皮质突变 (VPS) 和后脑囊皮质突变 (CPS),仍然是争论的主题.
研究的目的:
- 为了回顾性地比较临床特征,头骨成像和VPS与CPS的结果,在患有DWS相关水头症的儿童中.
- 为手术决策提供基于证据的见解,用于管理DWS相关的头.
主要方法:
- 对12名患有DWS相关头症 (Dandy-Walker形或变体) 的儿科患者的临床数据的回顾性分析.
- 患者接受了VPS (n=8) 或CPS (n=4) 的治疗.
- 评估结果使用埃文斯指数,维尼兰适应性行为量表 (VABS) 和评估头和小脑虫发育.
主要成果:
- 与CPS相比,VPS与统计学上显著的更好的临床结果,术后FOHR和VABS得分相关 (P<0.05).
- 在两个手术组 (P=0.018) 中,良好的小脑虫子发育与良好的结果有很强的相关性.
- 九名患者取得了良好的结果,三名患者取得了公平的结果;VPS组在心室大小和VABS分数方面显示出优异的结果.
结论:
- 对于儿科DWS相关的水头,VPS可能会导致与CPS相比更好的临床结果.
- 小脑虫的充分发育是影响这些患者手术成功的关键因素.
关键词:
孩子孩子孩子孩子孩子孩子囊关节突变 (cystoperitoneal shunt) 是一种关节突变,由囊关节突变组成的.丹迪 - 沃克综合征腹腔上腺突变 (Ventriculoperitoneal shunt) 已经开始使用.更多相关视频
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