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Updated: Jan 14, 2026

Measuring Mitochondrial Function of Naïve and Effector CD8 T Cells
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通过转录和代谢重编程,PARP抑制产生增强的CD8+中央记忆T细胞

Wael Traboulsi1, Pankaj Gaur1, Subhadip Kundu1

  • 1Center for Advanced Immunotherapy Research & The Loop Immuno-Oncology Research Lab, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington DC, USA.

Nature immunology
|January 12, 2026
PubMed
概括

聚基聚合酶 (PARP) 抑制增强CD8+T细胞,增强抗瘤免疫力. 这种重编程产生了优异的记忆T细胞,具有更好的回忆能力,用于更有效的癌症疗法.

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