金属-草药复合物作为新兴的治疗方法:化学,合成方法和药理学的见解
Biswajit Samantaray1, Sougat Suman Nayak1, Kalyani Jogimahanti1
1School of Pharmaceutical Sciences, Siksha 'O' Anusandhan University, Bhubaneswar, Odisha, 751033, India.
概括
金属-草药复合物 (MHCs) 将植物化合物和金属离子合并为增强的生物医学应用. 本综述探讨了MHC形成策略,突出了它们的多样化治疗潜力和在药物输送中的使用.
科学领域:
- 生物医学研究生物医学研究
- 药理学 药理学是指药理学的学科.
- 材料科学 材料科学 材料科学
背景情况:
- 金属-草药复合物 (MHCs) 是生物医学研究的一个新方法,它将植物化合物的治疗特性与金属离子结合起来.
- 大型HC提供了增强的生物可用性,生物环境友好性和广泛的生物活动,推动了该领域的快速增长.
研究的目的:
- 审查金属草本复合物 (MHC) 形成的各种策略.
- 为了识别用于MHC合成的金属和植物二次代谢物.
- 讨论影响MHC生产的因素及其药理影响.
主要方法:
- 对MHC形成和应用现有研究的文献综述.
- 分析植物二次代谢物 (例如,黄类,类,化合物) 作为金属离子的连接物.
- 检查用于创建MHCs的合成方法.
主要成果:
- 植物二次代谢产物作为有效的配体,合金属离子形成稳定的MHC.
- 形成MHC通常是一个单步过程,增强生物可用性.
- 大型肝癌体表现出广泛的药理活性,包括抗糖尿病,抗氧化,抗病毒,抗微生物,抗癌,抗炎,抗肝保护和神经保护作用.
结论:
- 大型瘤复合物是多功能化合物,在药物输送和生物医学研究中具有显著的潜力.
- 植物元素和金属离子的战略组合为开发新型,有效和生物相容的治疗剂开辟了新的途径.
- 对MHC合成和应用的进一步研究是有必要的,以充分利用它们的治疗能力.
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