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Updated: Jan 14, 2026

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基准测试共同折叠的方法,以预测共价蛋白-连接体复合体的结构

Tong-Han Zhang1, Jin-Tao Zhu2, Zhi-Xian Huang3

  • 1Peking-Tsinghua Center for Life Sciences, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, 100871, China.

Acta pharmacologica Sinica
|January 12, 2026
PubMed
概括

一个新的基准,CoFD-Bench,评估用于预测共价蛋白-连接体复合结构的方法. 同折叠模型显示出更高的准确性,但速度较慢,而经典对接是稳定的,但对于向的共价抑制剂设计来说不那么精确.

关键词:
基准测试 (benchmarking) 是一种比较的方法.共同折叠的方法同价复合体预测的预测有针对性的共价抑制剂.

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