黑素通过辐射后的代谢调节影响Bmi1+肠道干细胞命运

Xudan Lei1,2, Zhenni Xu1,2, Xiangjun Liu1

  • 1Precision Radiation in Oncology Key Laboratory of Sichuan Province, Sichuan Cancer Hospital & Institute, Sichuan Provincial Engineering Research Center of Tumor Organoids and Clinical Transformation, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.

PubMed
概括

黑素通过减少氧化应激和促进再生,在辐射损伤后保护肠道干细胞 (ISC). 这涉及调节线粒体代谢和Bmi1+细胞活动,提供了一种新的治疗方法.