儿童患者血液管理计划的评估:研究前/研究后的评估
Karen DiValerio Gibbs1,2, Adam Vogel1,3, Heidi Russell4
1Texas Children's Hospital, Houston, Texas, USA.
Transfusion
|January 13, 2026
概括
患者血液管理 (PBM) 在住院儿童中减少了红细胞 (RBC) 输血. 虽然输血相关不良事件 (TAEEs) 没有显著减少,但PBM在优化儿科输血实践方面表现有前途.
科学领域:
- 儿科血液学 儿科血液学
- 输血医学 输血医学
- 改善医疗保健质量 改善医疗保健质量
背景情况:
- 红细胞 (RBC) 输血至关重要,但存在输血相关不良事件 (TAEEs) 的风险.
- 患者血液管理 (PBM) 是一种多学科的方法来优化输血.
- 在儿科环境中PBM的影响需要进一步评估.
研究的目的:
- 评估PBM计划对儿科医院输血利用和TAEE的影响.
- 为了比较PBM实施前后的输血实践和结果.
主要方法:
- 追溯队列研究比较2015年 (PBM前) 和2019年 (PBM后).
- 包括4个月至18岁的儿童.
- 从电子健康记录中分析了输血利用率,RBC指南的遵守率和TAEE.
主要成果:
- 较少的住院治疗涉及PBM后输血 (p=0.02).
- 在PBM后观察到较低的输血前血红蛋白水平和较小的红细胞输血量 (p<0.01).
- 在TAEE发生率上没有发现统计学上显著的差异.
结论:
- 实施PBM可以有效地减少住院儿童的红细胞输血暴露.
- 需要进一步的研究来确认TAEE的减少,并评估PBM在儿科的成本效益.
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