长非编码RNA lncAPAT通过向核糖体蛋白L2222来促进动脉样硬化斑块的不稳定性

Rongxia Li1, Qiyue Zhang2, Yu Chen1

  • 1State Key Laboratory of Cardiovascular Disease, FuWai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

概括

一种新的长非编码RNA (lncRNA),IncAPAT,在冠状动脉疾病 (CAD) 患者中表达高. 通过抑制RPL22,LncAPAT促进巨细胞炎症和斑块不稳定,从而有助于心血管疾病的进展.

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