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Updated: Jan 14, 2026

Analysis of Somatic Hypermutation in the JH4 intron of Germinal Center B cells from Mouse Peyer's Patches
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STAT3 SH2 域 酸 661 突变激活免疫基因程序

Hye Kyung Lee1, Gyuhyeok Cho2, Jichun Chen3

  • 1Section of Genetics and Physiology, National Institute of Diabetes and Digestive and Kidney Diseases, US National Institutes of Health, Bethesda, Maryland, USA.

Journal of cellular and molecular medicine
|January 13, 2026
PubMed
概括

血液癌症中的STAT3 D661突变会导致各种功能增益效应. D661Y和D661V变种表现出强烈的活动,影响T细胞活力和免疫反应.

关键词:
D661变体的变体是什么在STAT3中,我们可以使用STAT3.功能获取 - 功能获取.血液学恶性瘤 血液学恶性瘤免疫系统的调节失调.

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