在治疗性低温期间和重新升温后,在低氧新生儿中使用各种回声心动图技术评估左心室功能
Natalia Brunets1, Veronika Brunets2, Agata Wójcik-Sęp3
1Department of Prematurity and Neonatal Pathology, Żelazna Medical Center Ltd St. Sophia's Specialist Hospital Medical Center,Poland.
Journal of ultrasonography
|January 13, 2026
概括
新生儿的治疗性低温会损害左心室功能,这体现在心心门速度和心脏输出量的减少. 与对照组相比,低温新生儿表现出腹痛功能障碍.
科学领域:
- 新生儿心脏病学 新生儿心脏病学
- 儿科重症监护室的重症监护室
- 心血管生理学心血管生理学
背景情况:
- 治疗性低温是新生儿缺氧缺血性脑病变的标准治疗方法.
- 它对心脏功能的影响,特别是左心室的表现,需要详细的评估.
研究的目的:
- 使用心声学评估治疗性低温的新生儿的左心室 (LV) 功能.
- 为了比较低温新生儿和非低温对照之间的心脏表现.
主要方法:
- 一个多中心的前性病例对照研究,涉及113名新生儿 (55名低温,58名对照).
- 在治疗性低温期间和重新升温后进行了心声图测量.
- 关键参数包括两头门的速度,心脏输出和LV尺寸.
主要成果:
- 低温新生儿在冷却过程中血压和心率有显著差异.
- 重温后的心率在低温组中较高.
- 在低温新生儿中观察到显著较低的 mitra 门速度 (A mv,E mv),心脏输出量,LV 扩张直径和缩外流.
- 较高的心肌性能指数和较低的E'/A'比率表明了低温组的透静功能障碍.
结论:
- 与对照组相比,接受治疗性低温症的新生儿表现出明显的全球左心室损伤.
- 心肌性能指数升高和E'/A'比率降低表明透缩功能障碍是低温的关键后果.
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