在健康的老年人中,可可黄在长时间坐着时保护内皮功能
Alessio Daniele1, Samuel J E Lucas1,2, Catarina Rendeiro1,2
1School of Sport, Exercise and Rehabilitation Sciences, University of Birmingham, Birmingham, UK. c.rendeiro@bham.ac.uk.
Food & function
|January 13, 2026
概括
在老年人中,可可黄可以预防坐着诱导的内皮功能障碍. 然而,黄醇在长时间坐着时没有影响血压变化.
科学领域:
- 心血管生理学心血管生理学
- 营养科学 营养科学
- 老年学是一门学科.
背景情况:
- 长时间坐着在老年人中很普遍,导致内皮功能和血压 (BP) 暂时受损.
- 在可可中发现的植物化合物黄醇,已知可以增强内皮功能并降低该人口群体的血压.
研究的目的:
- 为了确定是否急性可可黄摄入可以改善周围内皮功能和BP在健康的老年人长时间坐着期间.
- 为了研究高醇可可对长时间坐着后流介导扩张 (FMD) 和微血管血液动力学的影响.
主要方法:
- 一项随机,双盲,交叉,安慰剂控制的研究,涉及20名健康的老年人 (平均年龄72.4岁).
- 参与者在2个小时的坐姿前消耗了高醇 (695毫克) 或低醇 (5.6毫克) 的可可.
- 评估表面大腿动脉 (SFA) 和手臂动脉 (BA) FMD,高血压,以及坐着之前和之后的胃半径微血管血液动力学.
主要成果:
- 在低醇条件下,坐着显著减少了SFA和BA FMD.
- 高醇可可的摄入量阻止了口热的下降,保持了坐前的水平.
- 长时间坐着会增加心压和腹压血压,而这种效应并未通过摄入黄醇来减轻.
- 黄醇没有影响微血管血液动力学或坐着引起的肌肉氧化变化.
结论:
- 富含黄素可可的急性摄入可能是一种有效的营养策略,可以抵消老年人长时间坐着引起的内皮功能障碍.
- 在这个人群中,黄醇似乎不能减轻与长时间坐着相关的血压升高.
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