马斯5与马斯10:优化药剂师领导的临床心力衰竭实践中的坚持评估
Mirna Momčilović1,2, Iva Bužančić2,3, Boško Skorić4,5
11University Hospital Centre Zagreb, Zagreb Croatia.
Acta pharmaceutica (Zagreb, Croatia)
|January 13, 2026
概括
在心力衰竭 (HF) 中,药物坚持是至关重要的. 药物坚持报告尺度 (MARS-5和MARS-10) 有效地识别住院HF患者的不坚持,MARS-5提供了一个时间效率高的选择.
科学领域:
- 心脏病学 心脏病学
- 临床药房 临床药房
- 健康心理学 心理健康心理学
背景情况:
- 药物坚持对于有效的心力衰竭 (HF) 管理至关重要.
- 不坚持是普遍存在的,特别是在住院和晚期HF患者.
- 临床药剂师干预需要准确的评估工具.
研究的目的:
- 为了评估MARS-5和MARS-10在住院HF患者中的可靠性和得分关联.
- 评估这些工具在现实世界HF管理中的临床相关性.
- 确定MARS-5作为急性护理环境中的实用工具的实用性.
主要方法:
- 在药剂师主导的采访中使用MARS-5和MARS-10自我报告问卷.
- 分析了两个尺度之间的内部一致性可靠性和得分关联.
- 提出了四个临床案例,以在实践中说明依从性评估.
主要成果:
- 在MARS-5和MARS-10反应之间发现了强烈的关联 (科恩的kappa = 0.820,皮尔森的r = 0.899).
- 在MARS-5中可靠地发现了不依从性 (得分<20),与MARS-10 (得分 ≤8) 相比.
- 不坚持的患者经历了严重的并发症 (41.43%通过MARS-5,35.71%通过MARS-10).
结论:
- MARS-5和MARS-10是可靠和相关的工具,用于评估住院HF患者的药物坚持.
- 在急性情况下,MARS-5是一个实用的,时间效率高的选择,用于例行依从性评估.
- 临床药剂师在识别不服药症和启用干预措施以改善HF结果方面发挥着至关重要的作用.
相关概念视频
01:30Heart Failure V: Medical Management
209
Medical Management of Acute Decompensated Heart Failure (ADHF)The primary goals of therapy for patients hospitalized with acute decompensated heart failure (ADHF) include:Relieving symptomsOptimizing volume statusSupporting oxygenation and ventilationMaintaining cardiac output (CO) and end-organ perfusionIdentifying and addressing the cause of ADHFPreventing complicationsProviding patient education on factors precipitating HF exacerbationPlanning for dischargeOngoing monitoring and assessment...
209
01:22Heart Failure VI: Adjunct Therapies
246
Additional therapies for treating patients with heart failure (HF) may include procedural interventions, supplemental oxygen, the management of sleep disorders, and nutritional therapy.Procedural InterventionsImplantable Cardioverter-Defibrillator: For patients at risk of life-threatening arrhythmias due to severe left ventricular dysfunction, an Implantable Cardioverter-Defibrillator (ICD) can detect and terminate these arrhythmias, preventing sudden cardiac death and improving survival rates.
246
01:30Heart Failure VII: Nursing Interventions
410
The first step in nursing management of a patient with heart failure involves thoroughly assessing the patient's medical history.Subjective Data: Obtain the patient's medical history of coronary artery disease, hypertension, myocardial infarction, and symptoms like dyspnea, orthopnea, and paroxysmal nocturnal dyspnea.Objective Data: Conduct a physical examination to identify findings such as jugular vein distention, pulmonary crackles, tachycardia, murmurs, peripheral edema, and vital signs,...
410
01:22Heart Failure Drugs: β-Blockers
758
β-adrenergic antagonists, commonly known as β-blockers, block the effects of sympathetic neurotransmitters such as noradrenaline (NA) and adrenaline (ADR). They have several beneficial effects in heart failure treatment. They reduce heart rate, the force of contraction, and cardiac muscle relaxation. They also slow the atrial-ventricular conduction rate and raise the threshold for arrhythmias. The concentration of β-blockers determines their effects on bronchodilation,...
758
01:26Heart Failure Drugs: Inotropic Agents
1.2K
Positive inotropic agents are commonly used as the first line of treatment for heart failure. One such agent is digoxin, derived from the genus Digitalis, which has been known for centuries but effectively utilized since 1785. However, these cardiac glycosides can have potentially toxic effects due to their mechanism of action, which involves inhibiting Na+/K+-ATPase and increasing contractility. Digoxin is absorbed orally and distributed in various tissues, including the CNS. It has a long...
1.2K
01:28Mitral Regurgitation IV: Nursing Management
300
Mitral regurgitation (MR) is a condition where the mitral valve does not close properly, leading to the backward flow of blood from the left ventricle into the left atrium during systole. This condition can arise from various causes, including rheumatic fever, infective endocarditis, or degenerative valve disease. Effective nursing management is crucial to optimizing patient outcomes and involves comprehensive assessment and targeted interventions.Comprehensive Patient AssessmentA detailed...
300