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Updated: Jan 14, 2026

VDJ-Seq: Deep Sequencing Analysis of Rearranged Immunoglobulin Heavy Chain Gene to Reveal Clonal Evolution Patterns of B Cell Lymphoma
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慢性淋巴细胞白血病中克隆性血液形成的风景和演变

Othman Al-Sawaf1, Benjamin Nick Locher2, Friederike Christen3

  • 1University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany.

Blood
|January 13, 2026
PubMed
概括

克隆性血液形成 (CH) 在慢性淋巴细胞白血病 (CLL) 中很常见,并且与某些治疗方法的恶化结果有关. 然而,CH不会影响向治疗的预后,这表明有治疗特异性的影响.

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