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Updated: Jan 15, 2026

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由mTORC1在S61处的PDX1酸化将营养信号与β细胞功能和代谢疾病联系起来

Jialin Fan1, Xin Zhang1, Jinling Zhang1

  • 1Rutgers Cancer Institute, Rutgers, the State University of New Jersey, 195 Little Albany Street, New Brunswick, NJ 08901, USA; Department of Pharmacology, Robert Wood Johnson Medical School, Rutgers, the State University of New Jersey, 675 Hoes Lane, Piscataway, NJ 08854, USA.

Cell reports
|January 13, 2026
PubMed
概括

氨基酸通过mTORC1信号传递刺激胰腺和十二指肠本体盒1 (PDX1) 蛋白质的稳定性和活性. 这一途径对调节β细胞功能和增殖至关重要,影响糖尿病的发展.

关键词:
CP:代谢过程中的代谢.科普:分子生物学莫迪 (MODY) 的意思是说.氨基酸是氨基酸中的一种.糖尿病 糖尿病患者 糖尿病患者葡萄糖 葡萄糖 葡萄糖 是 一种过高胰岛素血症的发生胰岛素的胰岛素胰岛素是什么肝脏肥胖症 肝脏肥胖症在mTOROR中使用mTOR.营养素 营养素 营养素肥胖 肥胖 肥胖 肥胖 肥胖 肥胖 肥胖 肥胖在pdx1中,pdx1是什么意思一个β细胞β细胞.

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