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Updated: Jan 15, 2026

Combining Chemical Cross-linking and Mass Spectrometry of Intact Protein Complexes to Study the Architecture of Multi-subunit Protein Assemblies
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关于使用交叉连接质谱仪进行临床研究的可行性

Sung-Gun Park1, Ethan L Ostrom2, Sophia Liu3

  • 1Department of Genome Sciences, University of Washington, Seattle, Washington 98195 United States.

Journal of proteome research
|January 13, 2026
PubMed
概括

这项研究表明,定性交叉连接质谱法可以检测人体肌肉活检中的线粒体互动原子变化. 这种方法有助于理解与年龄和疾病相关的线粒体功能障碍.

关键词:
在OXPHOS复合体中.在XL-MS中使用XL-MS交叉链接是指交叉链接.一个死胡片的死胡.人类肌肉活组织检查互动的作用组.在内/间交叉链接的.线粒体中的线粒体.超级复杂的超级复杂的

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