在环境相关水平下,三种抗生素在生菜中的生物积累和不良影响
Jia Zheng1, Xiaoxue Pan1, Xiaojie Zhu1
1School of Resources and Environmental Engineering, Anhui University, Hefei, Anhui 230601, China.
Ecotoxicology and environmental safety
|January 13, 2026
概括
低水平的抗生素污染因恩罗夫洛克萨,硫甲和氧环素损害了生菜的生长,因为它破坏了光合作用并引起了氧化应激. 在植物中抗生素的积累是最小的,但观察到细胞损伤和抑制基因表达.
科学领域:
- 环境科学 环境科学
- 植物生物学 植物生物学
- 毒理学 毒理学 毒理学
背景情况:
- 抗生素污染是一个日益严重的环境问题.
- 关于低水平抗生素暴露对植物的影响的研究有限.
- 了解植物对常见抗生素的反应对于环境风险评估至关重要.
研究的目的:
- 调查恩洛夫洛克萨 (ENR),硫甲 (SM2) 和氧环素 (OTC) 对生菜 (Lactuca sativa L.) 的生物积累和不良影响.
- 评估环境相关的抗生素度 (1,10,100μg/L) 的植物反应.
主要方法:
- 菜暴露于三种不同度的抗生素中.
- 使用生物度因子 (BCF),根度因子 (RCF) 和转移因子 (TF) 来量化生物积累.
- 为了评估不良影响,进行了生理,生化,细胞和转录组分析.
主要成果:
- 在生菜组织中抗生素的积累是最小的 (BCFs,RCFs,TFs < 236 L/kg).
- 抗生素暴露扰乱了光合作用,降低了光合作用速率,诱导了氧化应激,并抑制了生长.
- 生物化学变化包括可溶性蛋白和糖的减少,抗氧化酶活性的增加和脂质过氧化的增加.
- 观察到细胞损伤,活性氧物种增加以及光合作用和抗氧化剂防御基因的下调.
- 凯格路径分析表明抑制能量代谢和应激反应路径.
结论:
- 环境相关的ENR,SM2和OTC度对生菜造成显著的不良影响,尽管生物积累最小.
- 抗生素污染对植物健康构成威胁,因为它损害了基本的生理过程和细胞完整性.
- 需要进一步的研究来了解农业系统中广泛的抗生素污染对生态的长期影响.
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