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Updated: Jun 14, 2026

Establishment and Characterization of Three Afatinib-resistant Lung Adenocarcinoma PC-9 Cell Lines Developed with Increasing Doses of Afatinib
09:38

Establishment and Characterization of Three Afatinib-resistant Lung Adenocarcinoma PC-9 Cell Lines Developed with Increasing Doses of Afatinib

Published on: June 26, 2019

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奥西默蒂尼布与或没有savolitinib作为MET异常,EGFR突变NSCLC的第一线治疗:随机二期试验 (FLOWERS)

Anna Li1, Wei-Neng Feng2, Juan Li3

  • 1Division 1 of Pulmonary Oncology, Guangdong Lung Cancer Institute, Guangdong Provincial Key Laboratory of Translational Medicine in Lung Cancer, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, China.

Nature communications
|January 13, 2026
PubMed
概括

与osimertinib单独相比,osimertinib和savolitinib的组合在治疗EGFR突变和MET异常的晚期非小细胞肺癌 (NSCLC) 中表现出更高的疗效. 这种组合疗法显示出更高的客观反应率和可管理的安全性.

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Profiling Sensitivity to Targeted Therapies in EGFR-Mutant NSCLC Patient-Derived Organoids

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Author Spotlight: Advancements in Molecular Biomarker Testing for Non-Squamous Non-Small Cell Lung Cancer07:59

Author Spotlight: Advancements in Molecular Biomarker Testing for Non-Squamous Non-Small Cell Lung Cancer

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