一项对患有腹腔疾病的儿童和健康对照者的认知功能进行比较研究
Sebastian Ludyga1, Laura Pedrini2, Laurin Sarbach2
1Department of Sport, Exercise and Health, University of Basel, Basel, Switzerland.
Scientific reports
|January 13, 2026
概括
在无质饮食 (GFD) 上,患有心脏病 (CD) 的儿童报告说,他们在学校的舒适性更好,欺凌程度更低. 认知表现和生活质量与健康对照相似,这表明GFD不会损害精神功能.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 神经心理学 神经心理学
- 微生物组研究 微生物组研究
背景情况:
- 病 (CD) 是一种免疫疾病,需要严格的无质饮食 (GFD).
- GFD可以影响生活质量 (QOL) 和肠道微生物组合.
- 肠-大脑轴的干扰与神经心理疾病有关.
研究的目的:
- 评估与健康对照组 (HC) 相比,患有CD的儿童和青少年的QOL和认知表现.
- 调查GFD对儿科CD患者精神健康和认知功能的影响.
主要方法:
- 一项涉及210名CD患者和234名HC患者的横截面研究,年龄在6-18岁之间.
- 使用问卷进行QOL评估.
- 通过Flanker任务进行认知性能评估.
主要成果:
- 慢性病患者报告说,学校的舒适度显著提高 (p=0.02) 和受欺凌的暴露率降低 (p=0.01).
- 在CD患者和HC患者之间没有观察到总体QOL或睡眠模式的显著差异.
- 弗兰克任务在准确度上没有差异,但CD患者反应时间较慢的趋势不显著 (p=0.19).
结论:
- 瑞士的儿科CD患者的QOL与HC相似.
- 在患有CD的儿童和青少年中,GFD似乎与认知功能受损无关.
- 进一步的研究可能会探索细微的认知差异和小儿CD的肠-大脑轴.
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