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Updated: Jan 15, 2026

Hyperinsulinemic-euglycemic Clamps in Conscious, Unrestrained Mice
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Hyperinsulinemic-euglycemic Clamps in Conscious, Unrestrained Mice

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乳酸激活的GPR81/FARP1信号驱动胰岛素独立的葡萄糖吸收和代谢控制

Yaxin Niu1, Shengmin Hu1, Yanfeng Zhang2

  • 1State Key Laboratory of Genetics and Development of Complex Phenotypes, Shanghai Key Laboratory of Metabolic Remodeling and Health, Institute of Metabolism and Integrative Biology, Drug Clinical Trial Center, Shanghai Xuhui Central Hospital, Zhongshan-Xuhui Hospital, Fudan University, Shanghai, China.

Cell research
|January 13, 2026
PubMed
概括

乳酸L作为葡萄糖吸收的胰岛素独立调节剂,减轻高血糖. 准乳酸受体GPR81为控制高血糖水平提供了一种新的治疗策略.

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