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Updated: Jan 15, 2026

Patient-Derived Tumor Explants As a "Live" Preclinical Platform for Predicting Drug Resistance in Patients
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利纳基巴特和潘布罗利祖马布在免疫检查点阻塞耐药的先进固体瘤中:一期1试验

Timothy A Yap1, Randy F Sweis2, Ulka Vaishampayan3

  • 1The University of Texas MD Anderson Cancer Center, Houston, TX, USA. TYap@mdanderson.org.

Nature medicine
|January 13, 2026
PubMed
概括

新型抗潜伏转化生长因子-β1 (TGFβ1) 抗体Linavonkibart在癌症治疗中与pembrolizumab结合使用时显示出可管理的安全性. 这种组合在耐抗编程细胞死亡蛋白1 (PD-1) 治疗的患者中显示出有效性.

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