高血压患者的药物坚持和功能性食物使用:一个横截面研究
Hidehiro Someko1,2,3,4, Takeo Nakayama5, Shiho Koizumi6
1Department of Healthcare Epidemiology, Graduate School of Medicine and Public Health, Kyoto University, Kyoto, Japan. hidehirosomeko@gmail.com.
概括
使用功能性食物治疗高血压的患者显示药物坚持率较低的风险更高. 这表明功能性食品的使用和对处方治疗的不理想遵守之间存在潜在的联系.
科学领域:
- 心血管健康 心血管健康
- 营养科学 营养科学
- 公共卫生 公共卫生
背景情况:
- 功能性食物越来越多地被患有慢性疾病 (如高血压) 的患者所采用.
- 在高血压患者中,功能性食物消费与药物坚持之间的关系尚不清楚.
研究的目的:
- 研究功能性食品的治疗使用与高血压成年人药物坚持之间的关联.
- 确定使用功能性食品治疗高血压是否与对处方抗高血压药物的较低坚持相关.
主要方法:
- 一项采用日本COVID-19和社会互联网调查 (JACSIS 2024) 的数据进行的横截面研究.
- 纳入标准:自报高血压的成年人服用抗高血压药物.
- 使用日本8项莫里斯基药物坚持度表 (MMAS-8) 评估药物坚持度,低坚持度定义为MMAS-8 <6.
主要成果:
- 该研究包括4063名接受治疗的高血压成年人 (586名功能性食品使用者,3477名非使用者).
- 在对共变量进行调整后,高血压的功能性食品使用与低药物坚持的风险增加有关 (风险比率1.24,95% CI 1.04-1.48).
- 在控制人口,社会经济和健康相关因素后,这种关联仍然很重要.
结论:
- 功能性食品在高血压患者的治疗使用可能与处方抗高血压治疗的低最佳坚持有关.
- 需要进一步的研究来探索这种关联和潜在的潜在机制.
- 横截面设计排除了因果推理,自我报告的数据可能会引入测量偏差.
相关概念视频
01:28Hypertension IV: Drug Therapy and Lifestyle Modifications
618
Multiple classes of antihypertensive medications are employed in treating hypertension. The most commonly recommended first-line treatments include:Thiazide Diuretics, such as chlorthalidone, increase sodium and water excretion from the body, reducing blood volume and blood pressure.Angiotensin-converting enzyme inhibitors, like lisinopril, block the conversion of angiotensin I to II, a potent vasoconstrictor lowering blood pressure.Angiotensin II Receptor Blockers (ARBs) prevent angiotensin II...
618
01:23Hypertension V: Nursing Management
355
The nursing management of hypertension involves accurately assessing symptoms, making a comprehensive nursing diagnosis, collaborating with patients to set goals, and implementing targeted interventions to mitigate the condition's impact and improve patient well-being.Comprehensive AssessmentThe initial step in nursing care for hypertension involves a thorough patient assessment. It includes evaluating symptoms such as headaches, dizziness, blurred vision, and previous hypertension episodes.
355
01:22Heart Failure VI: Adjunct Therapies
252
Additional therapies for treating patients with heart failure (HF) may include procedural interventions, supplemental oxygen, the management of sleep disorders, and nutritional therapy.Procedural InterventionsImplantable Cardioverter-Defibrillator: For patients at risk of life-threatening arrhythmias due to severe left ventricular dysfunction, an Implantable Cardioverter-Defibrillator (ICD) can detect and terminate these arrhythmias, preventing sudden cardiac death and improving survival rates.
252
01:26Atherosclerosis III: Management
319
Management of atherosclerosis involves an integrated strategy encompassing pharmacological treatment, surgical interventions, lifestyle changes, and nutrition therapy to address the multifactorial nature of the disease.Pharmacological TherapyA cornerstone of atherosclerosis management is the use of pharmacological agents. Statins, such as atorvastatin, are pivotal in inhibiting HMG-CoA reductase, an enzyme that catalyzes an initial step in cholesterol synthesis in the liver. This reduction in...
319
01:30Hypertension III: Clinical Manifestations and Diagnostic Studies
465
Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
465
01:15Bioavailability Study Design: Healthy Subjects Versus Patients
143
Bioavailability studies are essential for evaluating a drug's therapeutic efficacy and understanding its absorption patterns under various physiological conditions. Conducting such studies on target patient populations provides more relevant data by simulating real-world disease states. However, practical challenges often necessitate the use of young, healthy adult volunteers as study subjects.Patients may exhibit altered drug absorption patterns due to the effects of the disease itself,...
143