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循环T淋巴细胞子组作为固体瘤中免疫检查点抑制剂的生物标志物

Yuehong Kong1, Rongzheng Chen1, Junjun Zhang1

  • 1Center for Cancer Diagnosis and Treatment, Second Affiliated Hospital of Soochow University.

Clinical and experimental immunology
|January 14, 2026
PubMed
概括

循环T淋巴细胞子集显示出作为动态的,最少侵入性的生物标志物来预测固体瘤中免疫检查点抑制剂 (ICI) 治疗反应的前景. 这些生物标志物克服了当前方法的局限性,例如瘤突变负担 (TMB) 和PD-L1表达.

关键词:
循环免疫生物标志物循环免疫生物标志物免疫检查点抑制剂 免疫检查点抑制剂T细胞功能表型的功能表型这是T淋巴细胞子集.

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