在实践和临床试验中对免疫治疗的期望和知识:一个横截面研究
Beliz Bahar Karaoğlan1, Filiz Çay Şenler1,2
1Department of Medical Oncology, Ankara University Faculty of Medicine, Ankara, Türkiye.
Immunotherapy
|January 14, 2026
概括
患者往往缺乏关于免疫检查点抑制剂 (ICI) 的知识,尽管他们感觉有所了解. 参与临床试验可以增强乐观,但不能增强理解,这凸显了需要更好地教育患者的必要性.
科学领域:
- 在瘤学瘤学.
- 免疫治疗是一种免疫疗法.
- 患者教育 患者教育
背景情况:
- 关于免疫检查点抑制剂 (ICI),存在一个重要的知识期望差距.
- 有限的研究比较了门诊和临床试验中的患者理解.
研究的目的:
- 为了比较在门诊和临床试验中接受ICI的患者的知识,期望和决策偏好.
- 识别ICI的感知和实际理解之间的差异.
主要方法:
- 一项涉及124名实体瘤患者的横截面研究,这些患者接受了ICI治疗.
- 使用结构化问卷来评估ICI知识,副作用意识,治疗期望和决策偏好.
- 门诊 (OC) 和临床试验 (CT) 参与者之间的数据比较.
主要成果:
- 瘤学家是两个组的主要信息来源.
- CT患者觉得更多的信息 (62.5%对比34.2%),但客观知识在两者中都很差.
- CT患者报告了更高的治疗期望 (91.7%与64.5%) 和满意度 (75%与46.1%).
- 大多数患者更喜欢医生主导的决定停止ICI治疗.
结论:
- 患者往往缺乏关于ICI的准确知识,即使他们感觉有所了解.
- 参与临床试验可能会增加患者的乐观和满意度,但不一定会增加理解力.
- 针对性患者教育对于弥合知识与期望的差距和促进共享决策至关重要.
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