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Updated: Jan 15, 2026

Author Spotlight: Achieving High-Purity In Vitro Differentiation of Th17 Cells Using Cytokine Concentration Modulation
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Author Spotlight: Achieving High-Purity In Vitro Differentiation of Th17 Cells Using Cytokine Concentration Modulation

Published on: October 25, 2024

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CCL20-CCR6信号改变了代谢重编程,以促进致病的Th17细胞分化

Heikrujam Thoihen Meitei1,2, Neeraja Kulkarni1,2, Amey Shirolkar1

  • 1BRIC-National Centre for Cell Science, Ganeshkhind, SPPU Campus, Pune MH-411007, India.

iScience
|January 14, 2026
PubMed
概括

化学受体CCR6,当被CCL20激活时,驱动肠道炎症中的炎症性Th17细胞. 这一过程改变了T细胞代谢,增加了糖解和抑制了氧化酸化,提供了治疗点.

关键词:
生物科学 生物科学免疫系统的组成部分免疫学 免疫学 免疫学

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