相关实验视频

Updated: Jan 15, 2026

Mouse Model of Alloimmune-induced Vascular Rejection and Transplant Arteriosclerosis
07:05

Mouse Model of Alloimmune-induced Vascular Rejection and Transplant Arteriosclerosis

Published on: May 17, 2015

8.9K

主要组织相容性复杂I类匹配是必要的,但不足以在捐赠血液细胞移植后诱导对血管化复合异体移植的耐受性

Elin Manell1,2, M Esad Gunes1, Sarah Merl3

  • 1Department of Medicine, Columbia Center for Translational Immunology, Columbia University, New York, NY.

Transplantation direct
|January 14, 2026
PubMed
概括

主体组织相容性复合体 (MHC) 类I匹配对于成功的血管化复合体全移植 (VCA) 移植与血液细胞移植 (HCT) 移植至关重要. 一类匹配确保了移植的接受,而二类匹配影响了耐受性结果.

更多相关视频

Orthotopic Hind Limb Transplantation in the Mouse07:15

Orthotopic Hind Limb Transplantation in the Mouse

Published on: February 12, 2016

12.3K
Induction of Alloantigen-specific Anergy in Human Peripheral Blood Mononuclear Cells by Alloantigen Stimulation with Co-stimulatory Signal Blockade11:55

Induction of Alloantigen-specific Anergy in Human Peripheral Blood Mononuclear Cells by Alloantigen Stimulation with Co-stimulatory Signal Blockade

Published on: March 14, 2011

14.9K

相关概念视频

Tissue Transplantation01:24

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
894
Cell-mediated Immune Responses01:40

Cell-mediated Immune Responses

Overview
83.4K
Antigens Involved in Adaptive Immunity01:26

Antigens Involved in Adaptive Immunity

An antigen is any substance the immune system identifies as foreign and potentially harmful to the body, prompting an immune response. Antigens have two functional properties: immunogenicity and reactivity. Immunogenicity is the ability of an antigen to stimulate a specific immune response. At the same time, reactivity describes the antigen's ability to react with the cells and antibodies produced in response to it.
Complete Antigens
Complete antigens possess both immunogenicity and...
1.3K
Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
876