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在接受开放心脏手术的患者中,益生菌补充剂和术后抗氧化剂反应:一种随机对照试验

Fatemeh Mofidi¹, Sahar Kavand¹, Saeid Doaei^2,3

¹Clinical Research Development Unit, Loghman Hakim Hospital, Tehran.

Cardiovascular endocrinology & metabolism

|January 14, 2026

概括

益生菌补充剂在开放心脏手术患者中改善了抗氧化能力,显示出降低氧化应激的潜力. 需要进一步的研究来证实这些对术后康复的好处.

科学领域:

心血管外科心血管外科
营养科学营养科学
微生物组研究微生物组研究

背景情况:

氧化应激显著导致开心手术后的并发症.
益生菌正在研究它们对加强抗氧化防御和通过肠道微生物群调节减少炎症的潜力.
这项研究探讨了益生菌对接受开放心脏手术的患者氧化应激标志物的影响.

研究的目的:

评估益生菌补充剂对接受开放心脏手术的患者关键氧化应激生物标志物的影响.
为了确定益生菌是否可以增强总抗氧化能力 (TAC) 和影响手术后的甲酸 (MDA) 水平.

主要方法:

一项随机对照试验,涉及37名预定接受开放心脏手术的患者.
干预组接受了益生菌,对照组接受了安慰剂,手术前1天和手术后2周.
血MDA和TAC水平在基线和干预后使用ELISA和色度测定测量.

主要成果:

益生菌补充导致总抗氧化能力 (TAC) 的显著增加 (P < 0.001).
对照组在干预后显示了TAC水平的下降.
随着益生菌的使用,没有观察到马隆迪阿尔海德 (MDA) 水平的显著变化.

结论:

益生菌补充剂可以提高心脏开放手术患者的术后抗氧化剂状态.
益生菌作为一种辅助疗法,有望改善抗氧化防御和减轻氧化应激.
建议进行更大规模的临床试验,以验证这些发现并探索临床影响.

关键词:

抗氧化剂是一种抗氧化剂.心脏外科手术是一项心脏手术.马隆迪阿尔化物氧化应激是一种氧化应激.在术后的术后期.益生菌是一种益生菌.总抗氧化能力的抗氧化剂.

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