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使用磁性驱动的微变压器去除血栓

Fanan Wei¹, Shifan Zhan¹, Ligang Yao¹

¹School of Mechanical Engineering and Automation, Fuzhou University, Fuzhou, Fujian, China.

Macromolecular bioscience

|January 14, 2026

概括

一个新的磁性驱动微机器人 (MAMT) 为血栓性疾病提供了解决方案. 这种可重新配置的机器人可以导航血管和碎片,减少血管损伤并提高治疗安全性.

科学领域:

生物医学工程生物医学工程
材料科学材料科学材料科学
纳米技术纳米技术

背景情况:

血栓性疾病是全球死亡的主要原因之一.
目前用于血管干预的医疗机器人面临着诸如侵入性,血管壁压力和导航挑战等局限性.
需要灵活而可控制的系统来实现无血管导航和治疗.

研究的目的:

为治疗血栓性疾病引入一种磁性驱动微机器人 (MAMT),该机器人具有局部结构重新配置能力.
为了证明导航和血栓碎片化的双模式操作.
在模拟的血管环境中评估MAMT的安全性和有效性.

主要方法:

使用嵌入Fe3O4磁纳米粒子的形状记忆聚合物 (SMP) 制造微机器人.
利用由交替磁场 (AMF) 诱导的磁热效应进行结构转换.
在模拟的血液和血栓环境中测试结构切换,形状恢复和血栓清除.

主要成果:

在模拟的血液环境中,MAMT在148±8秒内证明了结构的转变,从棒状到螺旋形状.
在磁性启动时实现了92.11%的形状恢复比率.
成功清除52.7%的模拟血栓,展示了其碎片化能力.

结论:

磁性驱动微机器人 (MAMT) 提供了一个有希望的,可重新配置的解决方案,用于治疗血栓性疾病.
双模式功能 (导航和碎片化) 增强了治疗潜力.
与传统方法相比,降低了血管壁损伤的风险和改善了安全性.

关键词:

磁性微型机器人磁性微型机器人磁热效应是一种磁热效应.形状记忆形状记忆形状记忆结构转型结构转型

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