机械导向的线圈大小选择,用于内 Carotid 动脉瘤与流体结构相互作用的内 Carotid 动脉瘤
Jiakun Han1, Na Zhao2, Wei Li3
1College of Sciences, Xi'an University of Science and Technology, Xi'an, China.
概括
线圈大小影响大脑动脉瘤治疗. 最佳的线圈选择最大限度地减少了压力和位移,改善了内动脉动脉瘤的结果.
科学领域:
- 生物医学工程 生物医学工程
- 医学物理 医学物理
- 心血管研究研究心血管研究
背景情况:
- 线圈干预是脑动脉瘤的标准治疗方法.
- 线圈大小对动脉瘤血液动力学和机械学的影响仍然不清楚.
研究的目的:
- 为了研究不同的线圈大小对内动脉 (ICA) 动脉瘤的血液动力学和机械性质的影响.
- 在线圈干预中为机械导向的精密处理提供理论基础.
主要方法:
- 使用流体结构相互作用 (FSI) 方法与任意拉格朗-欧勒尔 (ALE) 方法.
- 模拟非牛顿血流和线性弹性动脉壁.
- 使用计算流体动力学 (CFD) 来预测结果.
主要成果:
- 增加线圈大小显著降低了动脉瘤壁剪压力 (WSS),时间平均 WSS (TAWSS) 和振荡式剪压指数 (OSI).
- 超大尺寸的线圈导致母动脉的压缩,邻近分支的TAWSS升高,以及动脉瘤壁应力度.
- 动脉瘤圆顶位移和·米塞斯应力最初减少,然后随着线圈大小的增加而增加.
结论:
- 适当的线圈大小对于最小化动脉瘤移位和压力至关重要,通过控制血液流速和流来控制动脉瘤的移位和压力.
- 建议根据动脉瘤形态和血液动力学进行个性化治疗计划.
- 这些发现支持在线圈干预中转向以机械为导向的精密处理.
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