自发冠状动脉解剖中的性别差异:iSCAD注册表的报告
Lori M Tam1, Sahar Naderi2, Gerald Chi3
1Providence Heart Institute Portland OR.
Journal of the American Heart Association
|January 14, 2026
概括
自发冠状动脉解剖 (SCAD) 在呈现和触发方面影响男性和女性不同. 虽然住院结果相似,但女性住院时间较长,男性更经常被处方他类药物和双重抗血小板治疗.
科学领域:
- 心脏病学 心脏病学
- 血管医学 血管医学
- 流行病学 流行病学
背景情况:
- 自发冠状动脉解剖 (SCAD) 是心肌梗塞的一个重要原因,主要影响中年女性.
- 关于SCAD在男性的特征和结果的数据有限.
研究的目的:
- 研究和比较男性和女性之间自发冠状动脉剖析 (SCAD) 的人口统计,临床表现,触发因素和住院结果.
- 为了确定SCAD患者基于性别的停留时间和出院药物的差异.
主要方法:
- 分析了来自多中心国际自发冠状动脉剖析 (iSCAD) 注册表 (2019-2023) 的数据.
- 人口统计,呈现特征,住院结果 (包括主要心血管不良事件),住院时间和出院药物在男性和女性之间进行了比较.
主要成果:
- 在1252名SCAD患者中,男性占6.4%;年龄与性别没有显著差异.
- 在触发因素 (女性的情绪压力,男性的身体炼) 和先前条件方面观察到显著的性别差异.
- 住院主要不良心血管事件类似,但女性住院时间较长;男性在出院时更经常被处方他类药物和双重抗血小板治疗.
结论:
- 在呈现,触发因素和与自发冠状动脉剖析 (SCAD) 相关的基线医疗条件中存在显著的基于性别的差异.
- 虽然住院结果相似,但女性住院时间较长.
- 出院药物治疗模式有所不同,男性更频繁地接受他类药物和双重抗血小板治疗.
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