在成年人中胃肠道症状的正常化 便秘与每日绿色果的消费:公开标签干预研究的协议
Jasjot Maggo1,2, Hwei Min Ng1,2, Simone Birgit Bayer1,2
1Department of Medicine, Christchurch, University of Otago, 2 Riccarton Avenue, Christchurch, 8011, New Zealand, 64 3 244 1074.
JMIR research protocols
|January 14, 2026
概括
绿色子可能会减轻腹部疼痛在患有便秘占主导地位的刺激性肠综合征 (IBS-C) 和功能性便秘 (FC) 的个体. 这项研究探讨了它的影响和潜在机制,为消化不适提供了潜在的自然缓解.
科学领域:
- 胃肠病学和营养科学 胃肠病学和营养科学
- 微生物组和免疫学研究研究
- 生理学和临床研究研究.
背景情况:
- 便秘 (IBS-C) 和功能性便秘 (FC) 显著损害生活质量.
- 目前对IBS-C和FC的治疗方法存在挑战.
- 绿色果显示作为一种天然药替代品的承诺,但其对腹痛和机制的有效性需要证实.
研究的目的:
- 研究每天食用绿色基维果对IBS-C和FC患者腹部疼痛和不适的影响.
- 探索与消化健康有关的绿色基维果摄入相关的潜在生理和生化机制.
- 评估绿色果对肠道运动,微生物群和炎症标志物的影响.
主要方法:
- 一项为期9周的,双臂,开放标签,安慰剂控制的随机研究,涉及60名IBS-C和FC患者.
- 干预组每天摄入2个绿色基维果4周;对照组摄入了与卡路里相匹配的马尔托德林安慰剂.
- 使用了经过验证的问卷,MRI检查结肠生理学,蓝色染料用于运输,血液/便样本和无线运动装置.
主要成果:
- 数据分析已经完成,预计到2026年4月将获得全部结果.
- 57名参与者使用治疗意向分析进行了分析.
- 这项研究提供了关于绿色基维果对IBS-C和FC患者生理和生化影响的综合数据集.
结论:
- 绿色果的消费可以有效地管理IBS-C和FC患者的腹痛.
- 这项研究为绿色桃促进消化舒适的机制提供了新的见解.
- 研究结果支持绿色基维果作为功能性胃肠道疾病的潜在自然治疗选择.
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