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Updated: Jan 17, 2026

Deciphering Molecular Mechanism of Histone Assembly by DNA Curtain Technique
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Deciphering Molecular Mechanism of Histone Assembly by DNA Curtain Technique

Published on: March 9, 2022

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对Bre1-Lge1和RNF20/RNF40-WAC相互作用的结构洞察力对于H2B无处不在至关重要

Meng Shi1, Xuejie Wang2, Hang Zhang3

  • 1Department of Biochemistry and Molecular Biology, Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), The province and ministry co-sponsored collaborative innovation center for medical epigenetics, State Key Laboratory of Experimental Hematology, Tianjin Medical University, Tianjin 300070, P.R. China.

Nucleic acids research
|January 14, 2026
PubMed
概括

基因素H2B (H2BUb1) 的单基因化对基因调节至关重要. 这项研究揭示了Bre1-Lge1和RNF20/RNF40-WAC复合体的结构洞察力,揭示了H2BUb1催化过程中至关重要的明显的静电相互作用.

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