三基编辑器催化了腺素,细胞素和关氨酸的和突变

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Updated: Jan 17, 2026

A Novel Saturation Mutagenesis Approach: Single Step Characterization of Regulatory Protein Binding Sites in RNA Using Phosphorothioates
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A Novel Saturation Mutagenesis Approach: Single Step Characterization of Regulatory Protein Binding Sites in RNA Using Phosphorothioates

Published on: August 21, 2018

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Youming Wu1, Jinxin Wang1, Ziyi Zhang2

  • 1State Key Laboratory of Common Mechanism Research for Major Diseases, Suzhou Institute of Systems Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Suzhou 215123, China.

Nucleic acids research
|January 14, 2026
PubMed
概括

我们开发了ACG基编辑器 (ACG-BEs),用于跨腺素,细胞素和关氨酸基的多重和突变发生. 这种DNA编辑工具增强了用于遗传查和治疗应用的DNA序列多样性.

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